Director of IT Operations

Nurix Therapeutics is a clinical stage biopharmaceutical company focused on the discovery, development, and commercialization of targeted protein degradation medicines, the next frontier in innovative drug design aimed at improving treatment options for patients with cancer and inflammatory diseases. Powered by a fully AI-integrated discovery engine capable of tackling any protein class, and coupled with unparalleled ligase expertise, Nurix’s dedicated team has built a formidable advantage in translating the science of targeted protein degradation into clinical advancements. Nurix aims to establish degrader-based treatments at the forefront of patient care, writing medicine’s next chapter with a new script to outmatch disease. Position Summary This role owns IT service delivery and vendor operations at Nurix. You will manage our internal service delivery team, oversee our managed service providers, and lead initiatives to improve how IT supports the business. Beyond running day-to-day operations, you will design and evolve Nurix's IT operating model as the company grows. The goal is not simply to manage vendors, It’s to create a service experience where employees get reliable help, problems get solved quickly, and IT enables rather than slows down the work.  You're empowered to restructure vendor relationships, change providers, or build internal capability as needed to achieve that outcome. This is a growth role. In Year 1, the focus is building a strong operational foundation. As that foundation matures, the role expands toward direct engagement with lines of business as an IT strategic partner. Responsibilities Service Delivery Lead the service delivery function, including the Service Delivery Manager and coordination with MSPs Own escalations and ensure employees receive timely, quality support Design and improve service delivery processes: documentation, knowledge management, meaningful metrics Evolve the operating model over time—assess what should be handled internally vs. through partners Manage on-prem infrastructure through MSPs; build internal capability if and when it makes sense Vendor Operations Own vendor relationships across the IT service provider portfolio Set clear expectations: scope, performance standards, accountability Lead contract negotiations and renewals to improve value Ensure vendors build our capability—we want to learn, not become dependent Rationalize the vendor portfolio as needed to improve outcomes Planning & Programs Develop a technology roadmap aligned with Nurix's clinical and business milestones, including sequencing and tradeoff rationale to support leadership decision-making Help leadership prioritize initiatives—frame options, clarify tradeoffs, recommend paths forward Lead cross-functional projects spanning infrastructure, security, and applications Support budget development, expense tracking, and financial reporting Collaboration Coordinate with Information Security on system hardening and compliance Work with Cloud Infrastructure on AWS and cloud-first initiatives Qualifications 10+ years in IT, including 5+ years in leadership or management roles Experience managing vendor relationships: contracts, performance, accountability Background in biotech, pharma, or life sciences Track record building roadmaps and driving cross-functional alignment Strong at translating business needs into actionable plans Effective communicator across technical and scientific audiences Bachelor's degree in a technical field, or equivalent experience Preferred Familiarity with GxP and regulated IT environments Experience with research platforms (ELN, LIMS, scientific data systems) AWS or cloud platform experience Product management or digital strategy background Coordinate with Information Security on system hardening and compliance Work with Cloud Infrastructure on AWS and cloud-first initiatives Fit with Nurix Culture and Values Strong team orientation; highly collaborative Ability to function in a dynamic environment Solutions and results-oriented focus Hands-on approach; resourceful and open to diverse points of view Salary Range: $ 214,637 – $244,431 Location: Brisbane, CA - Onsite  Nurix Therapeutics, Inc. is committed to protecting and respecting your privacy and personal information, including information collected by Nurix when you apply for a job with Nurix or in the course of your employment with Nurix.  By applying for a position at Nurix, you agree to our collection and use of personal information as described in our Privacy Policy (https://www.nurixtx.com/privacy-policy/).  Offices: San Francisco, California, United States (Brisbane, CA );