Vice President, Talent Management

“Mineralys Therapeutics is a clinical-stage biopharmaceutical company focused on developing medicines to target hypertension and related comorbidities such as chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated aldosterone.  Its initial product candidate, lorundrostat, is a proprietary, orally administered, highly selective aldosterone synthase inhibitor.  Mineralys is headquartered in Radnor, Pennsylvania. For more information, please visit https://mineralystx.com/. Follow Mineralys on LinkedIn, Twitter and Bluesky” Mineralys is a fully remote company. Vice President, Talent Management Position Summary The Vice President, Talent Management is a transformational leader who will design, build and lead a best-in-class, full-lifecycle talent organization at a pivotal moment in our company's history. As we transition from a development-stage company to a commercial enterprise, this leader will serve as the architect of our talent strategy — ensuring we attract, develop, engage and retain the exceptional people needed to bring life-changing therapies to patients. This is a role for a builder — someone who thrives in ambiguity, can construct scalable systems from the ground up and brings the vision, energy and operational excellence to transform talent into a true competitive advantage. The VP, Talent will be a trusted advisor to the organization and a champion of our culture and values across every dimension of the employee experience. Mineralys operates a hub-based remote model, with organizational anchors in Philadelphia, Boston and Boulder. This leader must be equally fluent in building distributed workforce practices and leveraging our hubs as cultural and community touchpoints. Key Responsibilities Talent Strategy & Leadership Develop and execute a comprehensive talent strategy aligned to the company's commercial launch priorities and long-range business plan Serve as a thought partner and advisor to the executive leadership team on all matters related to people, organizational design and workforce planning Lead a high-performing talent team, establishing clear roles, accountabilities and a culture of excellence within the function Establish talent metrics, KPIs and dashboards that provide data-driven insights to inform business decisions and demonstrate ROI of talent investments Talent Acquisition & Employer Brand Architect and lead a proactive, full-cycle talent acquisition function capable of scaling rapidly to support commercial launch hiring across commercial, medical affairs, market access and G&A functions Champion and amplify a compelling employer brand that distinguishes Mineralys in a competitive biotech talent market Develop a hub-anchored sourcing strategy centered around our Philadelphia, Boston and Boulder locations, while drawing from the broader national talent pool for roles suited to fully distributed workforce Develop strategic sourcing pipelines and partnerships with executive search firms to access top-tier talent across all three hub markets and beyond Onboarding & Integration Design a remote-first onboarding experience that intentionally builds cultural connection, peer relationships and role clarity in the absence of daily physical presence — including digital welcome journeys and manager-led integration rituals Establish role-specific onboarding tracks, with particular rigor for commercial field, medical and leadership hires, that reflect the complexity and compliance requirements of a commercial-stage biopharmaceutical organization Implement 30/60/90-day check-in frameworks and early-tenure engagement touchpoints to identify and address integration risks Performance Management & Talent Development Oversee the design of a modern performance management philosophy balances accountability with growth, grounded in regular feedback, meaningful coaching conversations and a shared commitment to continuous development Oversee a leadership development infrastructure including competency frameworks, succession planning and high-potential identification that grows our leaders from within Partner with functional heads to identify capability gaps and design targeted learning and development interventions, including both internal programs and curated external resources Oversee the establishment of career pathing frameworks across functions to create visibility into growth opportunities and improve retention of high performers Employee Experience & Culture Own the end-to-end employee experience with a relentless focus on creating an environment where talented people choose to do their best work Serve as a steward and amplifier of company culture — partnering with leadership to articulate, reinforce and evolve cultural norms as the organization grows Architect a remote employee experience that proactively addresses the unique challenges of distributed work — including digital fatigue, social isolation and access to leadership visibility — through purposeful virtual engagement programming and inclusive communication practices Establish remote-specific recognition practices and virtual moments of connection that build belonging and reinforce culture regardless of where employees are located Design and administer engagement surveys, pulse checks and listening mechanisms that generate actionable insight; ensure leaders are equipped and accountable to act on feedback Build recognition and rewards programs — both formal and informal — that celebrate achievement, reinforce values and create a culture of appreciation Workforce Planning & Organizational Effectiveness Partner with the HR Business Partner, Finance, and functional leaders to develop dynamic workforce plans that balance near-term hiring urgency with long-term organizational design discipline Advise on organizational structure decisions, span-of-control optimization and role design as the company scales through launch and beyond Develop and manage headcount and talent acquisition budgets with financial rigor and strategic prioritization Remote Work Infrastructure & Policy Establish and govern Mineralys' hub-based remote work policies, ensuring clarity, consistency and equity across all employee populations Design frameworks that define when and how hub presence is expected or encouraged, balancing flexibility with the cultural and collaborative benefits of in-person connection Total Rewards Partnership Collaborate closely with the Total Rewards function to ensure compensation, equity and benefits programs are competitive, equitable and aligned to talent attraction and retention goals Conduct regular competitive benchmarking against the biotech/biopharma peer set and make recommendations to maintain market competitiveness Compliance & Risk Management Ensure all talent practices comply with applicable employment laws and regulations Manage the regulatory complexity of a hub-based remote, multi-state workforce including state-by-state employer registration, varying leave and wage laws, pay transparency mandates and remote work policy governance Establish compliant, auditable processes for documentation, background screening, licensure verification and records management Qualifications Required 15+ years of progressive HR/talent leadership experience, with at least 7 years in a senior leadership role Demonstrated experience building or significantly scaling a talent function within a life sciences, biotech, or biopharma organization Experience supporting or leading talent strategy through a major organizational inflection point Proven track record of designing and implementing talent acquisition functions that successfully hired across commercial, scientific and operational functions under time pressure Deep expertise across the full talent lifecycle: acquisition, onboarding, performance management, development, engagement and retention Demonstrated experience building or leading a hub-based remote or fully distributed workforce, with a track record of maintaining high engagement, performance and retention in a virtual environment Data-driven mindset with proficiency in HRIS platforms and people analytics tools Exceptional communication skills — written and verbal — with the ability to inspire and align diverse audiences Bachelor's degree required; advanced degree in Human Resources, Organizational Psychology, Business Administration, or related field preferred Familiarity with field force hiring (sales, MSLs, market access) and the compliance considerations unique to pharmaceutical commercial organizations Preferred Background in organizational design and change management within a distributed workforce model Familiarity with the Philadelphia, Boston, and/or Boulder biotech talent markets SHRM-SCP, SPHR, or equivalent certification Travel This position requires up to 20% travel. Frequently travel is outside the local area and overnight. This position is eligible for standard Company benefits including medical, dental, vision, time off and 401K, as well as participating in Mineralys incentive plans are contingent on achievement of personal and company performance. Actual compensation may vary from posted hiring range based on geographic location, work experience, education, and/or skill level. US Salary Range:  $240,000 - $270,000 #LI-Remote   Offices: United States (Remote - US);