Director, IT

At Nautilus, we have a big and important mission: improve the health of millions by unleashing the potential of the proteome to accelerate drug development and enable a new world of precision and personalized medicine. We are developing a single-molecule protein analysis platform of unprecedented sensitivity, scale, and ease of use that we believe will democratize access to the proteome – one of the most dynamic and valuable sources of biological insight. To accomplish this, we are pursuing hard scientific problems with an entrepreneurial mindset and creating a world-class team of builders, innovators, and dreamers across a wide range of disciplines. As the Director of IT, you will drive the technological vision of our company, ensuring our systems are scalable, secure, and innovative. This role requires a forward-thinking leader who thrives in a fast-paced environment, can plan strategically, work tactically, and be hands-on in implementation. This position will report to the Senior Director of Software Engineering and IT, and will be located in San Carlos, CA. Responsibilities - Develop and implement IT strategies that align with organizational goals. - Combine strategic leadership with practical, daytoday technical engagement to drive reliable operations across infrastructure, hardware, networking, systems management, ensuring reliability, scalability, and performance. - Ensure data security, compliance, incidence response and disaster recovery protocols are in place. - Oversee IT budgets, vendor relationships, and procurement processes to ensure cost-effective and value-driven technology investments. - Provide regular updates to senior leadership on IT budget performance, risk posture, cybersecurity initiatives, and strategic priorities. - Identify and implement emerging technologies to improve business processes. - Implement AI strategy for increased organizational efficiency, decision-making, and operational outcomes. - Collaborate with software, operations, and legal teams to define and enforce enterprise-wide data governance policies and practices. - Partner with engineering, operations, finance, and software teams to enable technology-driven commercialization efforts - Drive the selection, integration and management of business systems (ERP, HRIS, PLM, CRM, etc.) crucial to operations and commercialization efforts. - Play an integral role in product definition, requirements specification and execution - Champion DevOps practices driving infrastructure-as-code (IaC), automation, continuous integration and continuous delivery (CI/CD) pipelines. - Inspire, mentor, and grow high-performing IT teams, fostering a culture of innovation, accountability, and cross-functional collaboration. - Set and communicate clear team priorities, ensuring alignment with company strategy and responsiveness to evolving business needs. - Build and reinforce scalable, actionable processes that empower teams to make informed decisions and deliver consistent results. - Foster collaboration between development and operations teams to streamline deployment processes and improve system reliability. - Navigate and lead teams through change, leveraging competitive insights and innovative thinking to adapt and thrive in dynamic environments. Qualifications - Bachelor’s degree in information technology, information systems, computer science or a related field. - 12+ years of IT experience, with 8+ years in a managerial role. - Expertise in cloud computing (preferably AWS and Azure), network design and infrastructure, and enterprise software. - Experience managing DevOps, driving IaC, automation, CI/CD pipelines, and collaboration between development and operations teams. - Experience deploying security and SaaS tools across organizations. - Proven experience deploying commercial products. - Deep understanding of IT architecture and cybersecurity. - Strong familiarity with software development practices. - Strong leadership and project management skills. - Experience with regulatory standards across data privacy, security, financial data management (GDPR, CCPA, HIPAA, SOX, ISO27001, etc.). - Requires bimonthly travel between office locations. Nautilus Team Culture - We are curious go-getters: this is a team of life-long learners who aren’t afraid to tackle the big challenges, and we embrace the journey. - We are detail-oriented: we do great science by working smart & with diligence where we learn from our trials and mistakes. - We are easy to work with: we want our workplace to be one where everyone can share their perspective and be treated with respect and kindness. #LI-MM1