Back to jobsNautilus Biotechnology
Manufacturing Technician
$71k – $104k/yr San Carlos, US on-site full time mid Mar 20, 2026
About this role
At Nautilus, we have a big and important mission: improve the health of millions by unleashing the potential of the proteome to accelerate drug development and enable a new world of precision and personalized medicine. We are developing a single-molecule protein analysis platform of unprecedented sensitivity, scale, and ease of use that we believe will democratize access to the proteome – one of the most dynamic and valuable sources of biological insight. To accomplish this, we are pursuing hard scientific problems with an entrepreneurial mindset and creating a world-class team of builders, innovators, and dreamers across a wide range of disciplines.
We are hiring a Manufacturing Technician to join our growing team. This technician will support the assembly and build of our instrument platform. This role will focus on hands-on assembly of complex electromechanical systems including mechanical structures, fluidic systems, and internal electrical wiring within a complex instrument chassis. The Manufacturing Technician will play a critical role in executing prototype and pilot builds, supporting the transition from engineering development to scalable manufacturing. The ideal candidate is comfortable working in a fast-paced development environment and has experience assembling complex scientific or electromechanical instrumentation.
Responsibilities
- Perform hands-on assembly of complex electromechanical instruments
- Assemble mechanical chassis, structural components, and internal subassemblies
- Install and route fluidic systems, including tubing, manifolds, pumps, and valves
- Install and route electrical wiring and harnesses within instrument enclosures
- Integrate mechanical, electrical, and fluidic subsystems within the instrument chassis
- Execute engineering prototype builds, design verification builds, and pilot production builds
- Follow detailed work instructions and assembly procedures
- Verify correct installation and alignment of components during assembly
- Escalate assembly issues or deviations to engineering or operations teams
- Support troubleshooting and rework activities when required
- Complete required manufacturing documentation including Device History Records (DHR), build travelers, traceability records
- Record serial numbers and part traceability information
- Document deviations or observations during builds
- Provide redlines or suggested improvements to assembly instructions
- Provide feedback to engineering and operations teams regarding build challenges or assembly issues
- Document observations that may improve manufacturability or assembly efficiency
- Support continuous improvement of assembly processes during pilot builds
Requirements
- 3–7+ years of experience assembling complex electromechanical systems
- Experience working with mechanical assemblies, fluidics, and electrical wiring
- Experience working in prototype, NPI, or pilot manufacturing environments
- Preferred industries include:
- Biotechnology / life sciences instrumentation
- Medical devices
- Analytical instrumentation
- Semiconductor equipment
- Aerospace instrumentation
Additional Requirements
- Strong attention to detail and assembly quality
- Ability to work independently after initial training
- Comfortable working in a fast-paced development environment
- Ability to identify and escalate build issues quickly
- Strong communication skills and ability to work cross-functionally with engineering teams